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The presence of both characteristics in one cell is rare and sets these highly specialized cells aside from the majority of the somatic cell populations. These unique properties make stem cells ideal targets for stem cell engineering to generate cells with wanted properties.
The laboratory studies pluripotent stem cells ES cells and iPS cells and adult stem cells hematopoietic stem cells and mesenchymal stem cells. Patient and disease specific iPS cells are obtained from somatic cells by reprogramming.
Hematopoietic stem Mature in aachen are differentiated into dendritic cells.
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Stem Cell Engineering Induced pluripotent stem cells iPS cells represent engineered stem cells, which are obtained by reprogramming of somatic cells with specific sets of transcription factors, such as Oct4, Sox2, Klf4 and c-Myc.
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Immunogenicity of iPS cells and iPS cell-derived cells remains controversial. Sertoli cells constitute the structural framework in testis and provide Horney single mom Leesville immune-privileged environment for germ cells.
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To meet the need of obtaining large s Mature in aachen iPS cells for disease modeling and drug development, a consortium of experts in engineering sciences and stem cell biology develops an automatic production system for iPS cells, referred to as StemCellFactory www. Selected Publications The role of Nav1.
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Meents, J. Pain, Jan 31Epub ahead of print.
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Differentiation of human induced pluripotent stem cells iPS cells and embryonic stem cells ES cells into dendritic cell DC subsets. Sontag, S.
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Bio-protocol 7, e Stem Cells 35,